Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseas...
Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease
About this item
Full title
Author / Creator
Cook, D R , Rossman, K L and Der, C J
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The aberrant activity of
R
as
ho
mologous (Rho) family small GTPases (20 human members) has been implicated in cancer and other human diseases. However, in contrast to the direct mutational activation of Ras found in cancer and developmental disorders, Rho GTPases are activated most commonly in disease by indirect mechanisms. One preval...
Alternative Titles
Full title
Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4875565
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4875565
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2013.362
