TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets
TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
The thymus produces γδ T cell subsets making either IFN-γ or IL-17. Silva-Santos and colleagues show that TCR signal strength within specific developmental windows is a major determinant of the generation of these γδ T cell subsets.
The mouse thymus produces discrete γδ T cell subsets that make either interferon-γ (IFN-γ) or interleukin 17 (IL-1...
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Full title
TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4875770
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4875770
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3424
