Small molecule activation of NOTCH signaling inhibits acute myeloid leukemia
Small molecule activation of NOTCH signaling inhibits acute myeloid leukemia
About this item
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Author / Creator
Ye, Qi , Jiang, Jue , Zhan, Guanqun , Yan, Wanyao , Huang, Liang , Hu, Yufeng , Su, Hexiu , Tong, Qingyi , Yue, Ming , Li, Hua , Yao, Guangmin , Zhang, Yonghui and Liu, Hudan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Aberrant activation of the NOTCH signaling pathway is crucial for the onset and progression of T cell leukemia. Yet recent studies also suggest a tumor suppressive role of NOTCH signaling in acute myeloid leukemia (AML) and reactivation of this pathway offers an attractive opportunity for anti-AML therapies.
N
-methylhemeanthidine chloride (N...
Alternative Titles
Full title
Small molecule activation of NOTCH signaling inhibits acute myeloid leukemia
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4876435
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4876435
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep26510
