Structural insights into inhibition of lipid I production in bacterial cell wall synthesis
Structural insights into inhibition of lipid I production in bacterial cell wall synthesis
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The crystal structure of the MraY enzyme from
Aquifex aeolicus
in complex with the naturally occurring nucleoside inhibitor muraymycin D2 (MD2) reveals that MraY undergoes a large conformational rearrangement near the active site after the binding of MD2, leading to the generation of a nucleoside-binding pocket and a peptide-binding site.
...
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Full title
Structural insights into inhibition of lipid I production in bacterial cell wall synthesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4882255
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4882255
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature17636