Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle
Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle
About this item
Full title
Author / Creator
Sommer, Andreas F. R. , Rivière, Lise , Qu, Bingqian , Schott, Kerstin , Riess, Maximilian , Ni, Yi , Shepard, Caitlin , Schnellbächer, Esther , Finkernagel, Malin , Himmelsbach, Kiyoshi , Welzel, Karin , Kettern, Nadja , Donnerhak, Christian , Münk, Carsten , Flory, Egbert , Liese, Juliane , Kim, Baek , Urban, Stephan and König, Renate
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Deoxynucleotide triphosphates (dNTPs) are essential for efficient hepatitis B virus (HBV) replication. Here, we investigated the influence of the restriction factor SAMHD1, a dNTP hydrolase (dNTPase) and RNase, on HBV replication. We demonstrated that silencing of SAMHD1 in hepatic cells increased HBV replication, while overexpression had the oppos...
Alternative Titles
Full title
Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle
Authors, Artists and Contributors
Author / Creator
Rivière, Lise
Qu, Bingqian
Schott, Kerstin
Riess, Maximilian
Ni, Yi
Shepard, Caitlin
Schnellbächer, Esther
Finkernagel, Malin
Himmelsbach, Kiyoshi
Welzel, Karin
Kettern, Nadja
Donnerhak, Christian
Münk, Carsten
Flory, Egbert
Liese, Juliane
Kim, Baek
Urban, Stephan
König, Renate
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4882586
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4882586
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep26616
