Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation
Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation
About this item
Full title
Author / Creator
Welte, Thomas , Kim, Ik Sun , Tian, Lin , Gao, Xia , Wang, Hai , Li, June , Holdman, Xue B. , Herschkowitz, Jason I. , Pond, Adam , Xie, Guorui , Kurley, Sarah , Nguyen, Tuan , Liao, Lan , Dobrolecki, Lacey E. , Pang, Lan , Mo, Qianxing , Edwards, Dean P. , Huang, Shixia , Xin, Li , Xu, Jianming , Li, Yi , Lewis, Michael T. , Wang, Tian , Westbrook, Thomas F. , Rosen, Jeffrey M. and Zhang, Xiang H.-F.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Myeloid-derived suppressor cells (MDSCs) play critical roles in primary and metastatic cancer progression. MDSC regulation is widely variable even among patients harbouring the same type of malignancy, and the mechanisms governing such heterogeneity are largely unknown. Here, integrating human tumour genomics and syngeneic mammary tumour models, we...
Alternative Titles
Full title
Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation
Authors, Artists and Contributors
Author / Creator
Kim, Ik Sun
Tian, Lin
Gao, Xia
Wang, Hai
Li, June
Holdman, Xue B.
Herschkowitz, Jason I.
Pond, Adam
Xie, Guorui
Kurley, Sarah
Nguyen, Tuan
Liao, Lan
Dobrolecki, Lacey E.
Pang, Lan
Mo, Qianxing
Edwards, Dean P.
Huang, Shixia
Xin, Li
Xu, Jianming
Li, Yi
Lewis, Michael T.
Wang, Tian
Westbrook, Thomas F.
Rosen, Jeffrey M.
Zhang, Xiang H.-F.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4884142
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4884142
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb3355