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Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4884142

Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

About this item

Full title

Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2016-06, Vol.18 (6), p.632-644

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Myeloid-derived suppressor cells (MDSCs) play critical roles in primary and metastatic cancer progression. MDSC regulation is widely variable even among patients harbouring the same type of malignancy, and the mechanisms governing such heterogeneity are largely unknown. Here, integrating human tumour genomics and syngeneic mammary tumour models, we...

Alternative Titles

Full title

Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4884142

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4884142

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb3355

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