A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative
A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Blebbistatin is a commonly used molecular tool for the specific inhibition of various myosin II isoforms both
in vitro
and
in vivo
. Despite its popularity, the use of blebbistatin is hindered by its poor water-solubility (below 10 micromolar in aqueous buffer) and blue-light sensitivity, resulting in the photoconversion of the molecule...
Alternative Titles
Full title
A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4886532
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4886532
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep26141
