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Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics

Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4887186

Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics

About this item

Full title

Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2016-06, Vol.126 (6), p.2049-2063

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

A eubiotic microbiota influences many physiological processes in the metazoan host, including development and intestinal homeostasis. Here, we have shown that the intestinal microbiota modulates inflammatory responses caused by sex steroid deficiency, leading to trabecular bone loss. In murine models, sex steroid deficiency increased gut permeabili...

Alternative Titles

Full title

Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4887186

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4887186

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI86062

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