Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting huma...
Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial
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Author / Creator
Trimble, Cornelia L, Prof , Morrow, Matthew P, PhD , Kraynyak, Kimberly A, PhD , Shen, Xuefei, PhD , Dallas, Michael, PhD , Yan, Jian, PhD , Edwards, Lance, MD , Parker, R Lamar, MD , Denny, Lynette, MD , Giffear, Mary, BS , Brown, Ami Shah, PhD , Marcozzi-Pierce, Kathleen, MA , Shah, Divya, MS , Slager, Anna M, MS , Sylvester, Albert J, MS , Khan, Amir, PhD , Broderick, Kate E, PhD , Juba, Robert J, MSCEP , Herring, Timothy A, MPH , Boyer, Jean, PhD , Lee, Jessica, MPH , Sardesai, Niranjan Y, PhD , Weiner, David B, Prof and Bagarazzi, Mark L, MD
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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More information
Scope and Contents
Contents
Summary Background Despite preventive vaccines for oncogenic human papillomaviruses (HPVs), cervical intraepithelial neoplasia (CIN) is common, and current treatments are ablative and can lead to long-term reproductive morbidity. We assessed whether VGX-3100, synthetic plasmids targeting HPV-16 and HPV-18 E6 and E7 proteins, delivered by electropor...
Alternative Titles
Full title
Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial
Authors, Artists and Contributors
Author / Creator
Morrow, Matthew P, PhD
Kraynyak, Kimberly A, PhD
Shen, Xuefei, PhD
Dallas, Michael, PhD
Yan, Jian, PhD
Edwards, Lance, MD
Parker, R Lamar, MD
Denny, Lynette, MD
Giffear, Mary, BS
Brown, Ami Shah, PhD
Marcozzi-Pierce, Kathleen, MA
Shah, Divya, MS
Slager, Anna M, MS
Sylvester, Albert J, MS
Khan, Amir, PhD
Broderick, Kate E, PhD
Juba, Robert J, MSCEP
Herring, Timothy A, MPH
Boyer, Jean, PhD
Lee, Jessica, MPH
Sardesai, Niranjan Y, PhD
Weiner, David B, Prof
Bagarazzi, Mark L, MD
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4888059
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4888059
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(15)00239-1
