Ultrasound-targeted hepatic delivery of factor IX in hemophiliac mice
Ultrasound-targeted hepatic delivery of factor IX in hemophiliac mice
About this item
Full title
Author / Creator
Anderson, C D , Moisyadi, S , Avelar, A , Walton, C B and Shohet, R V
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Ultrasound-targeted microbubble destruction (UTMD) was used to direct the delivery of plasmid and transposase-based vectors encoding human factor IX (hFIX) to the livers of hemophilia B (FIX−/−) mice. The DNA vectors were incorporated into cationic lipid microbubbles, injected intravenously, and transfected into hepatocytes by acoustic cavitation o...
Alternative Titles
Full title
Ultrasound-targeted hepatic delivery of factor IX in hemophiliac mice
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4891223
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4891223
Other Identifiers
ISSN
0969-7128
E-ISSN
1476-5462
DOI
10.1038/gt.2016.23
