Protective role for miR-9-5p in the fibrogenic transformation of human dermal fibroblasts
Protective role for miR-9-5p in the fibrogenic transformation of human dermal fibroblasts
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Excessive accumulation of extracellular matrix (ECM) proteins is the hallmark of fibrotic diseases, including skin fibrosis. This response relies on the activation of dermal fibroblasts that evolve into a pro-fibrogenic phenotype. One of the major players in this process is the cytokine transforming growth factor-β (TGF-β). MicroRNAs (miRNAs) are s...
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Full title
Protective role for miR-9-5p in the fibrogenic transformation of human dermal fibroblasts
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4891847
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4891847
Other Identifiers
ISSN
1755-1536
E-ISSN
1755-1536
DOI
10.1186/s13069-016-0044-2
