Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage
Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The development of metabolic tracers reveals that malic enzyme is the main contributor of NADPH production in differentiating adipocytes. During hypoxic conditions, the source of NADPH shifts to the oxidative pentose phosphate pathway.
The critical cellular hydride donor NADPH is produced through various means, including the oxidative pentose ph...
Alternative Titles
Full title
Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4891982
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4891982
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.2047
