Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors
Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors
About this item
Full title
Author / Creator
Tolani, B , Gopalakrishnan, R , Punj, V , Matta, H and Chaudhary, P M
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Primary effusion lymphoma (PEL) is an aggressive form of non-Hodgkin’s B-cell lymphoma associated with infection by Kaposi’s sarcoma-associated herpes virus (KSHV). (+)-JQ1 and I-BET151 are two recently described novel small-molecule inhibitors of BET bromodomain chromatin-associated proteins that have shown impressive preclinical activity in cance...
Alternative Titles
Full title
Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4892892
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4892892
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2013.242
