Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via tem...
Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The inflammasome NLRP3 is activated by pathogen associated molecular patterns (PAMPs) during infection, including RNA and proteins from influenza A virus (IAV). However, chronic activation by danger associated molecular patterns (DAMPs) can be deleterious to the host. We show that blocking NLRP3 activation can be either protective or detrimental at...
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Full title
Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4901306
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4901306
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep27912
