Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease
Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease
About this item
Full title
Author / Creator
Qiao, Dandi , Lange, Christoph , Beaty, Terri H. , Crapo, James D. , Barnes, Kathleen C. , Bamshad, Michael , Hersh, Craig P. , Morrow, Jarrett , Pinto-Plata, Victor M. , Marchetti, Nathaniel , Bueno, Raphael , Celli, Bartolome R. , Criner, Gerald J. , Silverman, Edwin K. , Cho, Michael H. , NHLBI Exome Sequencing Project , COPDGene Investigators and Lung GO
Publisher
United States: American Thoracic Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Thoracic Society
Subjects
More information
Scope and Contents
Contents
Genomic regions identified by genome-wide association studies explain only a small fraction of heritability for chronic obstructive pulmonary disease (COPD). Alpha-1 antitrypsin deficiency shows that rare coding variants of large effect also influence COPD susceptibility. We hypothesized that exome sequencing in families identified through a proban...
Alternative Titles
Full title
Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease
Authors, Artists and Contributors
Author / Creator
Lange, Christoph
Beaty, Terri H.
Crapo, James D.
Barnes, Kathleen C.
Bamshad, Michael
Hersh, Craig P.
Morrow, Jarrett
Pinto-Plata, Victor M.
Marchetti, Nathaniel
Bueno, Raphael
Celli, Bartolome R.
Criner, Gerald J.
Silverman, Edwin K.
Cho, Michael H.
NHLBI Exome Sequencing Project
COPDGene Investigators
Lung GO
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4910887
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4910887
Other Identifiers
ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.201506-1223OC
