Co-repressor CBFA2T2 regulates pluripotency and germline development
Co-repressor CBFA2T2 regulates pluripotency and germline development
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
A co-repressor protein, CBFA2T2, oligomerizes to stabilize its binding partner PRDM14 and the pluripotency factor OCT4 on chromatin, thus facilitating the transcriptional landscape underpinning the germline and pluripotent fate.
CBFA2T2 regulation of stem cell function
A core group of transcription factors are expressed both in pluripotent em...
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Full title
Co-repressor CBFA2T2 regulates pluripotency and germline development
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4911307
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4911307
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature18004
