Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of...
Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet
About this item
Full title
Author / Creator
Rocchi, Anna , Milioto, Carmelo , Parodi, Sara , Armirotti, Andrea , Borgia, Doriana , Pellegrini, Matteo , Urciuolo, Anna , Molon, Sibilla , Morbidoni, Valeria , Marabita, Manuela , Romanello, Vanina , Gatto, Pamela , Blaauw, Bert , Bonaldo, Paolo , Sambataro, Fabio , Robins, Diane M. , Lieberman, Andrew P. , Sorarù, Gianni , Vergani, Lodovica , Sandri, Marco and Pennuto, Maria
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Spinal and bulbar muscular atrophy (SBMA) is a neuromuscular disease caused by the expansion of a polyglutamine tract in the androgen receptor (AR). The mechanism by which expansion of polyglutamine in AR causes muscle atrophy is unknown. Here, we investigated pathological pathways underlying muscle atrophy in SBMA knock-in mice and patients. We sh...
Alternative Titles
Full title
Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet
Authors, Artists and Contributors
Author / Creator
Milioto, Carmelo
Parodi, Sara
Armirotti, Andrea
Borgia, Doriana
Pellegrini, Matteo
Urciuolo, Anna
Molon, Sibilla
Morbidoni, Valeria
Marabita, Manuela
Romanello, Vanina
Gatto, Pamela
Blaauw, Bert
Bonaldo, Paolo
Sambataro, Fabio
Robins, Diane M.
Lieberman, Andrew P.
Sorarù, Gianni
Vergani, Lodovica
Sandri, Marco
Pennuto, Maria
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4911374
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4911374
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-016-1550-4
