Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and...
Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques
About this item
Full title
Author / Creator
Li, Hui , Wang, Shuyi , Kong, Rui , Ding, Wenge , Lee, Fang-Hua , Parker, Zahra , Kim, Eunlim , Learn, Gerald H. , Hahn, Paul , Policicchio, Ben , Brocca-Cofano, Egidio , Deleage, Claire , Hao, Xingpei , Chuang, Gwo-Yu , Gorman, Jason , Gardner, Matthew , Lewis, Mark G. , Hatziioannou, Theodora , Santra, Sampa , Apetrei, Cristian , Pandrea, Ivona , Alam, S. Munir , Liao, Hua-Xin , Shen, Xiaoying , Tomaras, Georgia D. , Farzan, Michael , Chertova, Elena , Keele, Brandon F. , Estes, Jacob D. , Lifson, Jeffrey D. , Doms, Robert W. , Montefiori, David C. , Haynes, Barton F. , Sodroski, Joseph G. , Kwong, Peter D. , Hahn, Beatrice H. and Shaw, George M.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Most simian–human immunodeficiency viruses (SHIVs) bearing envelope (Env) glycoproteins from primary HIV-1 strains fail to infect rhesus macaques (RMs). We hypothesized that inefficient Env binding to rhesus CD4 (rhCD4) limits virus entry and replication and could be enhanced by substituting naturally occurring simian immunodeficiency virus Env res...
Alternative Titles
Full title
Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques
Authors, Artists and Contributors
Author / Creator
Wang, Shuyi
Kong, Rui
Ding, Wenge
Lee, Fang-Hua
Parker, Zahra
Kim, Eunlim
Learn, Gerald H.
Hahn, Paul
Policicchio, Ben
Brocca-Cofano, Egidio
Deleage, Claire
Hao, Xingpei
Chuang, Gwo-Yu
Gorman, Jason
Gardner, Matthew
Lewis, Mark G.
Hatziioannou, Theodora
Santra, Sampa
Apetrei, Cristian
Pandrea, Ivona
Alam, S. Munir
Liao, Hua-Xin
Shen, Xiaoying
Tomaras, Georgia D.
Farzan, Michael
Chertova, Elena
Keele, Brandon F.
Estes, Jacob D.
Lifson, Jeffrey D.
Doms, Robert W.
Montefiori, David C.
Haynes, Barton F.
Sodroski, Joseph G.
Kwong, Peter D.
Hahn, Beatrice H.
Shaw, George M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4914158
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4914158
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1606636113
