Progerin, the protein responsible for the Hutchinson-Gilford progeria syndrome, increases the unrepa...
Progerin, the protein responsible for the Hutchinson-Gilford progeria syndrome, increases the unrepaired DNA damages following exposure to ionizing radiation
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Publisher
England: BioMed Central
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Language
English
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England: BioMed Central
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Progerin, the protein responsible for the Hutchinson-Gilford Progeria Syndrome (HGPS), is a partially deleted form of nuclear lamin A, and its expression has been suggested as a cause for dysfunctional nuclear membrane and premature senescence. To examine the role of nuclear envelop architecture in regulating cellular aging and DNA repair, we used...
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Full title
Progerin, the protein responsible for the Hutchinson-Gilford progeria syndrome, increases the unrepaired DNA damages following exposure to ionizing radiation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4917958
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4917958
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ISSN
1880-7062,1880-7046
E-ISSN
1880-7062
DOI
10.1186/s41021-015-0018-4
