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Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly pr...

Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4921848

Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly process of α-hemolysin

About this item

Full title

Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly process of α-hemolysin

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-06, Vol.6 (1), p.28254, Article 28254

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

α-hemolysin (Hla) is a self-assembling extracellular protein secreted as a soluble monomer by most
Staphylococcus aureus
strains and is an essential virulence factor for the pathogenesis of various
S. aureus
infections. Here, we show that curcumin (CUR), a natural compound with weak anti-
S. aureus
activity, can inhibit the hemoly...

Alternative Titles

Full title

Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly process of α-hemolysin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4921848

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4921848

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep28254

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