Calibrating genomic and allelic coverage bias in single-cell sequencing
Calibrating genomic and allelic coverage bias in single-cell sequencing
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Artifacts introduced in whole-genome amplification (WGA) make it difficult to derive accurate genomic information from single-cell genomes and require different analytical strategies from bulk genome analysis. Here, we describe statistical methods to quantitatively assess the amplification bias resulting from whole-genome amplification of single-ce...
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Full title
Calibrating genomic and allelic coverage bias in single-cell sequencing
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4922254
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4922254
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7822
