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Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosa...

Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4928055

Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas

About this item

Full title

Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-06, Vol.6 (1), p.28953-28953, Article 28953

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Osteosarcoma is a rare disease diagnosed as malignant bone tumor. It is generally refractory to chemotherapy, which contributes to its poor prognosis. The reversal of chemoresistance is a major clinical challenge to improve the prognostic outcome of osteosarcoma patients. We developed a tumor-specific replication-competent oncolytic adenovirus, OBP...

Alternative Titles

Full title

Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4928055

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4928055

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep28953

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