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Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4931679

Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

About this item

Full title

Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-07, Vol.6 (1), p.29290-29290, Article 29290

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Obesity is the result of a long-term positive energy balance in which caloric intake overrides energy expenditure. This anabolic state results from the defective activity of hypothalamic neurons involved in the sensing and response to adiposity. However, it is currently unknown what the earliest obesity-linked hypothalamic defect is and how it orch...

Alternative Titles

Full title

Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4931679

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4931679

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep29290

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