Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4⁺ T-Cell Effector F...
Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4⁺ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation
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United States: Oxford University Press
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English
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Publisher
United States: Oxford University Press
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Helminth-infected individuals possess a higher risk of developing tuberculosis, but the precise immunologic mechanism of Mycobacterium tuberculosis control remains unclear. We hypothesized that a perturbation of the M. tuberculosis-specific CD4⁺ T-cell response weakens the ability of macrophages to contain M. tuberculosis. We exposed peripheral blo...
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Full title
Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4⁺ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4936644
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4936644
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ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1093/infdis/jiw156