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Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4⁺ T-Cell Effector F...

Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4⁺ T-Cell Effector F...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4936644

Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4⁺ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation

About this item

Full title

Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4⁺ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation

Publisher

United States: Oxford University Press

Journal title

The Journal of infectious diseases, 2016-08, Vol.214 (3), p.479-488

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

Helminth-infected individuals possess a higher risk of developing tuberculosis, but the precise immunologic mechanism of Mycobacterium tuberculosis control remains unclear. We hypothesized that a perturbation of the M. tuberculosis-specific CD4⁺ T-cell response weakens the ability of macrophages to contain M. tuberculosis. We exposed peripheral blo...

Alternative Titles

Full title

Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4⁺ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4936644

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4936644

Other Identifiers

ISSN

0022-1899

E-ISSN

1537-6613

DOI

10.1093/infdis/jiw156

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