TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influ...
TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus
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Author / Creator
Sakai, Kouji , Ami, Yasushi , Nakajima, Noriko , Nakajima, Katsuhiro , Kitazawa, Minori , Anraku, Masaki , Takayama, Ikuyo , Sangsriratanakul, Natthanan , Komura, Miyuki , Sato, Yuko , Asanuma, Hideki , Takashita, Emi , Komase, Katsuhiro , Takehara, Kazuaki , Tashiro, Masato , Hasegawa, Hideki , Odagiri, Takato and Takeda, Makoto
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Influenza A and B viruses show clear differences in their host specificity and pandemic potential. Recent studies have revealed that the host protease TMPRSS2 plays an essential role for proteolytic activation of H1, H3, and H7 subtype strains of influenza A virus (IAV)
in vivo
. IAV possessing a monobasic cleavage site in the haemagglutinin...
Alternative Titles
Full title
TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4937385
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4937385
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep29430