Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression
Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Costanzo and colleagues find, by reconstitution of repetitive centromeric DNA replication in
Xenopus
egg extracts, that replication is facilitated by suppression of ATR-mediated checkpoint signalling and formation of DNA loop structures.
Half of the human genome is made up of repetitive DNA
1
. However, mechanisms underlying replicat...
Alternative Titles
Full title
Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4939857
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4939857
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb3344
