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Navigating the bone marrow niche: translational insights and cancer-driven dysfunction

Navigating the bone marrow niche: translational insights and cancer-driven dysfunction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4947935

Navigating the bone marrow niche: translational insights and cancer-driven dysfunction

About this item

Full title

Navigating the bone marrow niche: translational insights and cancer-driven dysfunction

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Rheumatology, 2016-03, Vol.12 (3), p.154-168

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
The bone marrow niche supports the integration of two major organ systems — the skeleton and the marrow
The niche is a unique microenvironment that is crucial for haematopoietic stem cell quiescence
Important features of the niche include its cellular components, hypoxia, extracellular matrices, cytokines and growth factors, and...

Alternative Titles

Full title

Navigating the bone marrow niche: translational insights and cancer-driven dysfunction

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4947935

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4947935

Other Identifiers

ISSN

1759-4790

E-ISSN

1759-4804

DOI

10.1038/nrrheum.2015.160

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