Navigating the bone marrow niche: translational insights and cancer-driven dysfunction
Navigating the bone marrow niche: translational insights and cancer-driven dysfunction
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Key Points
The bone marrow niche supports the integration of two major organ systems — the skeleton and the marrow
The niche is a unique microenvironment that is crucial for haematopoietic stem cell quiescence
Important features of the niche include its cellular components, hypoxia, extracellular matrices, cytokines and growth factors, and...
Alternative Titles
Full title
Navigating the bone marrow niche: translational insights and cancer-driven dysfunction
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4947935
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4947935
Other Identifiers
ISSN
1759-4790
E-ISSN
1759-4804
DOI
10.1038/nrrheum.2015.160