The hypoxia-inducible factor-1α activates ectopic production of fibroblast growth factor 23 in tumor...
The hypoxia-inducible factor-1α activates ectopic production of fibroblast growth factor 23 in tumor-induced osteomalacia
About this item
Full title
Author / Creator
Publisher
China: Baltimore Veterans Administration Medical Center, Baltimore, MD, USA
Journal title
Language
English
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Publication information
Publisher
China: Baltimore Veterans Administration Medical Center, Baltimore, MD, USA
More information
Scope and Contents
Contents
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome in which ectopic production of fibroblast growth factor 23 (FGF23) by non-malignant mesenchymal tumors causes phosphate wasting and bone fractures. Recent studies have implicated the hypoxia-inducible factor-1α (HIF-1α) in other phosphate wasting disorders caused by elevated FGF23,...
Alternative Titles
Full title
The hypoxia-inducible factor-1α activates ectopic production of fibroblast growth factor 23 in tumor-induced osteomalacia
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4948305
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4948305
Other Identifiers
ISSN
2095-4700
E-ISSN
2095-6231
DOI
10.1038/boneres.2016.11
