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Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4955715

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

About this item

Full title

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2016-08, Vol.17 (8), p.966-975

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Nikolich-Žugich and colleagues describe a unique subset of human T cells with a naive phenotype and the ability to rapidly produce cytokines in response to engagement of the T cell antigen receptor.
The number of naive T cells decreases and susceptibility to new microbial infections increases with age. Here we describe a previously unknown subse...

Alternative Titles

Full title

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4955715

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4955715

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3483

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