DNA binding triggers tetramerization of the glucocorticoid receptor in live cells
DNA binding triggers tetramerization of the glucocorticoid receptor in live cells
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Transcription factors dynamically bind to chromatin and are essential for the regulation of genes. Although a large percentage of these proteins appear to self-associate to form dimers or higher order oligomers, the stoichiometry of DNA-bound transcription factors has been poorly characterized in vivo. The glucocorticoid receptor (GR) is a ligand-r...
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Full title
DNA binding triggers tetramerization of the glucocorticoid receptor in live cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4961135
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4961135
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1606774113