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DNA binding triggers tetramerization of the glucocorticoid receptor in live cells

DNA binding triggers tetramerization of the glucocorticoid receptor in live cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4961135

DNA binding triggers tetramerization of the glucocorticoid receptor in live cells

About this item

Full title

DNA binding triggers tetramerization of the glucocorticoid receptor in live cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (29), p.8236-8241

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Transcription factors dynamically bind to chromatin and are essential for the regulation of genes. Although a large percentage of these proteins appear to self-associate to form dimers or higher order oligomers, the stoichiometry of DNA-bound transcription factors has been poorly characterized in vivo. The glucocorticoid receptor (GR) is a ligand-r...

Alternative Titles

Full title

DNA binding triggers tetramerization of the glucocorticoid receptor in live cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4961135

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4961135

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1606774113

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