Enhanced biglycan gene expression in the adipose tissues of obese women and its association with obe...
Enhanced biglycan gene expression in the adipose tissues of obese women and its association with obesity-related genes and metabolic parameters
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Extracellular matrix (ECM) remodeling dynamically occurs to accommodate adipose tissue expansion during obesity. One non-fibrillar component of ECM, biglycan, is released from the matrix in response to tissue stress; the soluble form of biglycan binds to toll-like receptor 2/4 on macrophages, causing proinflammatory cytokine secretion. To investiga...
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Full title
Enhanced biglycan gene expression in the adipose tissues of obese women and its association with obesity-related genes and metabolic parameters
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4964581
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4964581
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep30609
