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Donor dendritic cell–derived exosomes promote allograft-targeting immune response

Donor dendritic cell–derived exosomes promote allograft-targeting immune response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4966303

Donor dendritic cell–derived exosomes promote allograft-targeting immune response

About this item

Full title

Donor dendritic cell–derived exosomes promote allograft-targeting immune response

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2016-08, Vol.126 (8), p.2805-2820

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The immune response against transplanted allografts is one of the most potent reactions mounted by the immune system. The acute rejection response has been attributed to donor dendritic cells (DCs), which migrate to recipient lymphoid tissues and directly activate alloreactive T cells against donor MHC molecules. Here, using a murine heart transpla...

Alternative Titles

Full title

Donor dendritic cell–derived exosomes promote allograft-targeting immune response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4966303

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4966303

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI84577

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