Enhanced mitochondrial glutamine anaplerosis suppresses pancreatic cancer growth through autophagy i...
Enhanced mitochondrial glutamine anaplerosis suppresses pancreatic cancer growth through autophagy inhibition
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Cancer cells use precursors derived from tricarboxylic acid (TCA) cycle to support their unlimited growth. However, continuous export of TCA cycle intermediates results in the defect of mitochondrial integrity. Mitochondria glutamine metabolism plays an essential role for the maintenance of mitochondrial functions and its biosynthetic roles by refi...
Alternative Titles
Full title
Enhanced mitochondrial glutamine anaplerosis suppresses pancreatic cancer growth through autophagy inhibition
Authors, Artists and Contributors
Author / Creator
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4967856
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4967856
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep30767
