Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS
Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Endothelial cells (ECs) are critical mediators of blood pressure (BP) regulation, primarily via the generation and release of vasorelaxants, including nitric oxide (NO). NO is produced in ECs by endothelial NO synthase (eNOS), which is activated by both calcium (Ca2+)-dependent and independent pathways. Here, we report that intracellular Ca2+ relea...
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Full title
Maintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4968706
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4968706
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1608859113
