Disruption of dmc1 Produces Abnormal Sperm in Medaka (Oryzias latipes)
Disruption of dmc1 Produces Abnormal Sperm in Medaka (Oryzias latipes)
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Author / Creator
Chen, Ji , Cui, Xiaojuan , Jia, Shaoting , Luo, Daji , Cao, Mengxi , Zhang, Yunsheng , Hu, Hongling , Huang, Kaiyao , Zhu, Zuoyan and Hu, Wei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
DMC1 is a recombinase that is essential for meiotic synapsis. Experiments in extensive species of eukaryotes have indicated the independent role of DMC1 in repairing double strand breaks (DSBs) produced during meiosis I. Mutation of
dmc1
in mice and human often leads to obstacles in spermatogenesis and male sterility. Here, we report on the d...
Alternative Titles
Full title
Disruption of dmc1 Produces Abnormal Sperm in Medaka (Oryzias latipes)
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4969596
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4969596
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep30912
