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Immunoregulatory soluble CTLA-4 modifies effector T-cell responses in systemic lupus erythematosus

Immunoregulatory soluble CTLA-4 modifies effector T-cell responses in systemic lupus erythematosus

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4973056

Immunoregulatory soluble CTLA-4 modifies effector T-cell responses in systemic lupus erythematosus

About this item

Full title

Immunoregulatory soluble CTLA-4 modifies effector T-cell responses in systemic lupus erythematosus

Publisher

England: BioMed Central Ltd

Journal title

Arthritis research & therapy, 2016-08, Vol.18 (1), p.180-180, Article 180

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The inhibitory CTLA-4 molecule is a crucial regulator of immune responses and a target for therapeutic intervention in both autoimmunity and cancer. In particular, CTLA-4 is important in controlling antigen-specific immunity, including responses to autoantigens associated with autoimmune disease. Here, we investigate cytokine responses to a range o...

Alternative Titles

Full title

Immunoregulatory soluble CTLA-4 modifies effector T-cell responses in systemic lupus erythematosus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4973056

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4973056

Other Identifiers

ISSN

1478-6362,1478-6354

E-ISSN

1478-6362

DOI

10.1186/s13075-016-1075-1

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