Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus
Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The authors find that optogenetic stimulation of melanin-concentrating hormone (MCH)-expressing neurons in the lateral hypothalamus selectively extends the duration of paradoxical sleep episodes in mice. Activation of MCH fibers in the tuberomammillary nucleus leads to the release of GABA and a similar increase in paradoxical sleep stability.
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Full title
Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4974078
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4974078
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3522
