PKM2 enhances chemosensitivity to cisplatin through interaction with the mTOR pathway in cervical ca...
PKM2 enhances chemosensitivity to cisplatin through interaction with the mTOR pathway in cervical cancer
About this item
Full title
Author / Creator
Zhu, Haiyan , Wu, Jun , Zhang, Wenwen , Luo, Hui , Shen, Zhaojun , Cheng, Huihui and Zhu, Xueqiong
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Pyruvate kinase M2 (PKM2) is a key driver of aerobic glycolysis in cancer cells and has been shown to be up-regulated by mTOR
in vitro
. Our previous proteomic profiling studies showed that PKM2 was significantly upregulated in cervical cancer tissues after treatment with neoadjuvant chemotherapy (NACT). Whether PKM2 expression predicts cispl...
Alternative Titles
Full title
PKM2 enhances chemosensitivity to cisplatin through interaction with the mTOR pathway in cervical cancer
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4974606
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4974606
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep30788
