HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma
HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Class I histone deacetylases (HDACs) have been reported to be overexpressed in clear cell renal cell carcinoma (ccRCC), whereas the expression of class II HDACs is unknown.
Four isogenic cell lines C2/C2VHL and 786-O/786-OVHL with differential VHL expression are used in our studies. Cobalt chloride is used to mimic hypoxia in vitro. HIF-2α knock...
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HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4977667
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4977667
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-016-2604-7