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DNA methylation on N6-adenine in mammalian embryonic stem cells

DNA methylation on N6-adenine in mammalian embryonic stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4977844

DNA methylation on N6-adenine in mammalian embryonic stem cells

About this item

Full title

DNA methylation on N6-adenine in mammalian embryonic stem cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2016-04, Vol.532 (7599), p.329-333

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

It has been widely accepted that 5-methylcytosine is the only form of DNA methylation in mammalian genomes. Here we identify
N
6
-methyladenine as another form of DNA modification in mouse embryonic stem cells.
Alkbh1
encodes a demethylase for
N
6
-methyladenine. An increase of
N
6
-methyladenine levels in
Alkbh1...

Alternative Titles

Full title

DNA methylation on N6-adenine in mammalian embryonic stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4977844

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4977844

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature17640

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