Alternative splicing of interleukin-33 and type 2 inflammation in asthma
Alternative splicing of interleukin-33 and type 2 inflammation in asthma
About this item
Full title
Author / Creator
Gordon, Erin D. , Simpson, Laura J. , Rios, Cydney L. , Ringel, Lando , Lachowicz-Scroggins, Marrah E. , Peters, Michael C. , Wesolowska-Andersen, Agata , Gonzalez, Jeanmarie R. , MacLeod, Hannah J. , Christian, Laura S. , Yuan, Shaopeng , Barry, Liam , Woodruff, Prescott G. , Ansel, K. Mark , Nocka, Karl , Seibold, Max A. and Fahy, John V.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Type 2 inflammation occurs in a large subgroup of asthmatics, and novel cytokine-directed therapies are being developed to treat this population. In mouse models, interleukin-33 (IL-33) activates lung resident innate lymphoid type 2 cells (ILC2s) to initiate airway type 2 inflammation. In human asthma, which is chronic and difficult to model, the r...
Alternative Titles
Full title
Alternative splicing of interleukin-33 and type 2 inflammation in asthma
Authors, Artists and Contributors
Author / Creator
Simpson, Laura J.
Rios, Cydney L.
Ringel, Lando
Lachowicz-Scroggins, Marrah E.
Peters, Michael C.
Wesolowska-Andersen, Agata
Gonzalez, Jeanmarie R.
MacLeod, Hannah J.
Christian, Laura S.
Yuan, Shaopeng
Barry, Liam
Woodruff, Prescott G.
Ansel, K. Mark
Nocka, Karl
Seibold, Max A.
Fahy, John V.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4978244
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4978244
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1601914113
