Elimination of microglia improves cognitive function following cranial irradiation
Elimination of microglia improves cognitive function following cranial irradiation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cranial irradiation for the treatment of brain cancer elicits progressive and severe cognitive dysfunction that is associated with significant neuropathology. Radiation injury in the CNS has been linked to persistent microglial activation, and we find upregulation of pro-inflammatory genes even 6 weeks after irradiation. We hypothesize that depleti...
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Full title
Elimination of microglia improves cognitive function following cranial irradiation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4981848
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4981848
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep31545
