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A reactivity-based probe of the intracellular labile ferrous iron pool

A reactivity-based probe of the intracellular labile ferrous iron pool

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4990480

A reactivity-based probe of the intracellular labile ferrous iron pool

About this item

Full title

A reactivity-based probe of the intracellular labile ferrous iron pool

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2016-09, Vol.12 (9), p.680-685

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Editorial Summary
A reactivity-based probe containing an iron-sensitive 1,2,4-trixolane ring conjugated to a small molecule payload combined with a high-throughput immunofluorescence assay enables the selective detection of labile intracellular ferrous iron.
Improved methods for studying intracellular reactive Fe(
II
) are of significan...

Alternative Titles

Full title

A reactivity-based probe of the intracellular labile ferrous iron pool

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4990480

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4990480

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.2116

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