Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detectio...
Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Starting from only a few cells, current whole genome amplification (WGA) methods provide enough DNA to perform massively parallel sequencing (MPS). Unfortunately, all current WGA methods introduce representation bias which limits detection of copy number aberrations (CNAs) smaller than 3 Mb. A recent WGA method, called TruePrime single cell WGA, us...
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Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4992833
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4992833
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2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep31825