Log in to save to my catalogue

Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detectio...

Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detectio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4992833

Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing

About this item

Full title

Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-08, Vol.6 (1), p.31825-31825, Article 31825

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Starting from only a few cells, current whole genome amplification (WGA) methods provide enough DNA to perform massively parallel sequencing (MPS). Unfortunately, all current WGA methods introduce representation bias which limits detection of copy number aberrations (CNAs) smaller than 3 Mb. A recent WGA method, called TruePrime single cell WGA, us...

Alternative Titles

Full title

Performance of a TthPrimPol-based whole genome amplification kit for copy number alteration detection using massively parallel sequencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4992833

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4992833

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep31825

How to access this item