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Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions

Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4994004

Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions

About this item

Full title

Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-08, Vol.6 (1), p.31506-31506, Article 31506

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Glomerular mesangial cells (MCs) hypertrophy is one of the earliest pathological abnormalities in diabetic nephropathy (DN), which correlates with eventual glomerulosclerosis. This study aimed to investigate the therapeutic role of miRNA in diabetic glomerular MCs hypertrophy and synthesis of extracellular matrix (ECM). Microarray analysis revealed...

Alternative Titles

Full title

Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4994004

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4994004

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep31506

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