Tumor-induced stromal reprogramming drives lymph node transformation
Tumor-induced stromal reprogramming drives lymph node transformation
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The contribution of stromal cells to the microenvironment of tumor-draining lymph nodes is poorly characterized. By comparative transcriptional analysis, Shields and colleagues find that tumors induce the stromal reprogramming of key pathways that affect the structure and function of such lymph nodes.
Lymph node (LN) stromal cells, particularly...
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Full title
Tumor-induced stromal reprogramming drives lymph node transformation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4994871
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4994871
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3492