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TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-2...

TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-2...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4995376

TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21

About this item

Full title

TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-08, Vol.6 (1), p.32231-32231, Article 32231

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

TGF-β1, upregulated in keloid tissue, promotes the proliferation, collagen formation and differentiation of dermal fibroblasts. miR-21 is one of microRNAs first found in human genome. The aim of our study is to explore the mechanisms of miR-21 in TGF-β1-induced scar fibroblasts proliferation and transdifferentiation. In the present study, first we...

Alternative Titles

Full title

TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4995376

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4995376

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep32231

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