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Oestradiol synthesized by female neurons generates sex differences in neuritogenesis

Oestradiol synthesized by female neurons generates sex differences in neuritogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4995407

Oestradiol synthesized by female neurons generates sex differences in neuritogenesis

About this item

Full title

Oestradiol synthesized by female neurons generates sex differences in neuritogenesis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-08, Vol.6 (1), p.31891-31891, Article 31891

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Testosterone produced by the foetal testis is converted by male neurons to oestradiol, which masculinizes neuronal morphology. Female neurons are known to synthesize oestradiol in absence of exogenous testosterone. However, the role of neuronal oestradiol on the differentiation of foetal female neurons is unknown. Here we show that, due to endogeno...

Alternative Titles

Full title

Oestradiol synthesized by female neurons generates sex differences in neuritogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4995407

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4995407

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep31891

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