Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis
Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Data from multiple sclerosis (MS) and the MS rodent model, experimental autoimmune encephalomyelitis (EAE), highlighted an inflammation-dependent synaptopathy at the basis of the neurodegenerative damage causing irreversible disability in these disorders. This synaptopathy is characterized by an imbalance between glutamatergic and GABAergic transmi...
Alternative Titles
Full title
Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5002118
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5002118
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-016-0686-4
