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Near-atomic cryo-EM structure of PRC1 bound to the microtubule

Near-atomic cryo-EM structure of PRC1 bound to the microtubule

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5003279

Near-atomic cryo-EM structure of PRC1 bound to the microtubule

About this item

Full title

Near-atomic cryo-EM structure of PRC1 bound to the microtubule

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (34), p.9430-9439

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Proteins that associate with microtubules (MTs) are crucial to generate MT arrays and establish different cellular architectures. One example is PRC1 (protein regulator of cytokinesis 1), which cross-links antiparallel MTs and is essential for the completion of mitosis and cytokinesis. Here we describe a 4-Å–resolution cryo-EM structure of monomeri...

Alternative Titles

Full title

Near-atomic cryo-EM structure of PRC1 bound to the microtubule

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5003279

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5003279

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1609903113

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